As part of the research project F2437 on behalf of BAuA (Federal Institute for Occupational Safety and Health) FoBiG is currently analysing existing methods for deriving occupational limit values (OELs) and develops proposals for updates and harmonisation. With the now published “Synthesis report” all discussion papers are now available at BAuA’s website.

If you have questions or comments, please contact Klaus Schneider.

As part of a research project on behalf of BAuA (Federal Institute for Occupational Safety and Health) FoBiG is currently analysing existing methods for deriving occupational limit values (OELs) and develops proposals for updates and harmonisation. Further project reports are now available at BAuA’s website. These reports deal with the extrapolation steps
• Time extrapolation
• Interspecies extrapolation
• Intraspecies extrapolation
We analyse these steps and derive distributions based on newly created databases. In a further report we discuss the methodology to calculate so-called “Human Equivalent Concentrations” (HEC) for interspecies extrapolation in the lower respiratory tract in case of particle exposure.

If you have any questions, please contact Klaus Schneider.

Since 17 September 2020, EFSA's final risk assessment on the four most important PFAS in food in terms of quantity has been available. The group TWI (tolerable weekly intake) for all four substances (perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA) and perfluorohexane sulfonic acid (PFHxS)) of 4.4 ng/kg bw per week was derived based on the impairment of the immune response as the most sensitive endpoint. This new risk assessment makes it necessary to revise the guidance values or health orientation values (GOW) for PFAS in drinking water. The draft European Drinking Water Directive also provides for a regulation of PFAS in drinking water. In a recommendation, the Federal Environment Agency has already pointed out the resulting challenges for analytical laboratories.

For further information please contact Ulrike Schuhmacher-Wolz.

Following respective recommendations by ECHA the European Commission included 11 further substances into REACH Annex XIV, among them several borate compounds and UV stabilisers (benzotriazole derivatives (Commission Regulation (EU) 2020/171 of 6 February 2020). With the Annex XIV listing these substances will not be allowed to be used in the future unless an application for authorisation for specific uses is submitted. For several substances, short dates for submitting authorisations were set (end of 2021).

Name                                                                                                       EC #                                 CAS #
1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear      271-093-5                         68515-50-4

Dihexyl phthalate                                                                                 201-559-5                         84-75-3

1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters                            -                                        -
or mixed decyl and hexyl and octyl diesters
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)    

Trixylyl phosphate                                                                               246-677-8                          25155-23-1

Sodium perborate, perboric acid, sodium salt                                      -                                         -
Perboric acid, sodium salt
EC No.: 234-390-0 | CAS No.: 11138-47-9
Sodium perborate EC No.: 239-172-9 | CAS No.: 15120-21-5   

Sodium peroxometaborate                                                                  231-556-4                           7632-04-4

5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-                   -                                          -
1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-
5-methyl-1,3-dioxane [2]
covering any of the individual stereoisomers of [1] and [2] or
any combination thereof       

2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol (UV-328)                   247-384-8                           25973-55-1

2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol (UV-327)            223-383-8                          3864-99-1

2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (UV-350)   253-037-1                          36437-37-3

2-benzotriazol-2-yl-4,6-di-tert-butylphenol (UV-320)                           223-346-6                           3846-71-7

For questions regarding REACH authorisation please contact Klaus Schneider.

On July 1, 2020 Klaus Schneider handed over the office of FoBiG managing director to Jan Oltmanns. We would like to deeply thank Klaus Schneider for more than 8 years of excellent leadership and are pleased that he will continue to work energetically for FoBiG! Jan Oltmanns has worked as a scientist for FoBiG for more than 30 years– 11 of which as partner. The carefully prepared handover within the company gives reason to hope for many more years of good management at FoBiG.